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Mutations of the KISS1 Gene in Disorders of Puberty

Because of this, it is important to distinguish between measurements of the intact hormone (responsible for endocrine actions) or the sum of the intact hormone and its metabolites, reflecting the total L-cell secretion and therefore also the possible neural actions

[16] The principal AOD9604 studies cited here did not establish a complete AOD9604-to-UCP1 pathway or demonstrate direct induction of UCP1 transcription, UCP1 activity, white-adipose browning, or functional thermogenesis

Many users find this dose sufficient for significant improvement

But, absent human trials, its next to impossible to know what it does in the body