Overall tolerability of the treatment was good, with the most common side effect being nausea, particularly during treatment initiation or dose adjustments, while diarrhea was reported by 5% of patients, which was dose-dependent and easily managed
A total of 195 differentially expressed circRNAs were identified in METH-treated mice compared to saline-treated mice, with 88 upregulated and 107 downregulated 122
Ectopic expression of wild-type Np63, but not the transactivation-defective mutant (R304W), markedly increased intracellular serine level (Fig
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