A 2022 systematic review examining antioxidant interventions for liver disease concluded that NAC showed "moderate to strong evidence" for improving liver function markers, while oral glutathione (non-liposomal forms) had "limited evidence" of clinical efficacy
b, Immunoblot analysis of the expression of GPX4, ACSL4, and LPCAT3 ( n = 3)
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Among these, glutathione (GSH), a tripeptide antioxidant, has demonstrated versatile and potent ROS-scavenging properties ( Graphene oxide (GO) has emerged as a promising nanoplatform due to its high surface area, rich surface chemistry, and excellent biocompatibility when properly functionalized ( Precise localization of nanocarriers to the injury site is crucial for therapeutic efficacy