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Aspirin reduces the risk of heart attacks and strokes, which can also occur in people with NAION
Additionally, Fe2+ binds to the N-terminal domain of A, destabilizing its helical structure and promoting peptide aggregation by enhancing peptide-peptide interactions (37)
Side effects become more predictable
Tirzepatide increases heart rate modestly (average 24 bpm in clinical trials), while growth hormone effects on cardiac function require monitoring in susceptible individuals
Summary Cardiovascular effects of liraglutide, semaglutide and tirzepatide can be mediated by EAT inflammation
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