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This rationale aligns with emerging priorities in cardio-oncology, where patients treated with anthracyclines face substantial risk of cardiotoxicity and where metabolic interventions may be especially valuable, particularly in cancers such as breast, ovarian, and prostate, in which cachexia is uncommon but treatment-related weight gain is frequent 26,27

However, many people remain asymptomatic in the early stages, with the condition detected only through routine blood tests

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The fraction of weight lost as fat-free mass depends on baseline adiposity, age, sex, diet, protein intake, inactivity, resistance training, metabolic state, and the rate and duration of weight loss

While GLP - 1 drugs have been used so far primarily to manage diabetes and clinical obesity defined as having a body mass index (BMI) above 30 the EY-Parthenon survey confirms that the user base is changing as it grows to include more people with moderate weight problems and those who just want to look slimmer