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doi:10.1002/jcp.25693 [PubMed] Narvaez J, Maldonado G, Intriago M, et al

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(Source: Novo Nordisk) In September 2024: Eli Lilly reported positive Phase 3 results for retatrutide, a novel triple GLP-1/GIP/glucagon receptor agonist, demonstrating an average weight loss of 24.2% at 48 weeks in adults with obesity, representing the highest weight loss achieved with any pharmacological agent to date and approaching bariatric surgery efficacy

In this review, we will examine the phenomenon of receptor dimerization with a focus on the role of the ghrelin receptor in such dimers and how this knowledge can aid in devising improved treatments for such disorders as Parkinsons disease, schizophrenia, obesity, depression, and diabetes

Inhibition of research-subject glutathione S-transferases by curcumin and analogues