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Additionally, BCSCs isolated from primary human breast cancers possess the advanced metastasis potential and the CD70+ subpopulations appear to preferentially mediate lung-specific metastasis by enhancing self-renewal potential (125)

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Combined hypothesis for synergy in migration: If BPC-157 supports the transcriptional/signaling environment that enables migration and survival, while TB-500 supports actin-associated motility and the physical execution of migration, then co-administration may increase both (1) the number of cells that can participate effectively and (2) the speed/efficiency with which they reach the injury site and organize the repair scaffold

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