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Animal experiments can directly measure grip strength, muscle cross-sectional area, and specific molecular markers

Effects of tirzepatide on circulatory overload and end-organ damage in heart failure with preserved ejection fraction and obesity: a secondary analysis of the SUMMIT trial

Sex as a biological variable: we utilized only male rats to maximize the satellite cell yield per gram of muscle tissue and individual animal (Figure 1d,f and supplementary Figure 1a) and male mice to examine the preventive effect of oral administration of glutathione trisulfide (GSSSG) and lipoic acid trisulfide (LASSS) (Figure 2e) on disuse-induced nitration-dysfunction of ECM-bound HGF