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Without uridine, the cell compensates for pyrimidine shortage by over-activating ATP-consuming salvage pathways (UCK2, TK1, dCK), which potentially drives mitochondrial biogenesis to generate more ATP for these phosphorylation reactions 63

On the other hand, IGF-IR may trigger EMT via STAT3, FAK, and NF-kB [67, 68]

A study conducted in high cholesterol diet-supplemented Wistar rats that received 50, 150, and 300 mg/kg bodyweight of PsP derived from G

TorzewskiJHeiglFZimmermannOWagnerFSchumannCHettichRet alFirst-in-man: case report of selective c-reactive protein apheresis in a patient with SARS-CoV-2 infection

Reference Schapira, AHV 2006, Mitochondrial Disease, The Lancet , vol