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Clark RH et al

N Engl J Med 380, 347-357 (2019)

Ist zu wenig L-Carnitin im Krper vorhanden, werden die Fettsuren nicht mehr optimal in die Mitochondrien transportiert und knnen somit nicht in Energie umgewandelt werden

However, despite the anti-diabetic and anti-obesity functions, of these dual and triple agonists, the long-term safety, cardiovascular, and renal benefits of these multi-target therapies need further validation