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Counteraction of GLP-1 effect on gastric emptying by co-infusion with prokinetic drug erythromycin during a liquid test meal diminished GLP-1s ability to decrease postprandial hyperglycemia in patients with T2DM (153)

co-administration of pyridoxine has been shown to reduce the blood levels of phenobarbital and phenytoin, possibly diminishing their anticonvulsant efficacy

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Even more impressive, allulose may influence key metabolic hormonesputting it in a category far beyond ordinary sweeteners