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FEBS Lett 245:105109 Abeysinghe RD, Roberts PJ, Cooper CE et al (1996) The environment of the lipoxygenase iron binding site explored with novel hydroxypyridinone iron chelators
10.1210/en.2011-1795 24 DavisE
Similar restrictions apply to liraglutide (Saxenda) under NICE TA664
HPLC Purity Analysis Confirms the peptide is 99% pure Mass Spectrometry Verifies the exact molecular identity Heavy Metals Screening Lead, arsenic, cadmium & mercury Pass Endotoxins (LPS) Bacterial endotoxin levels Pass Sterility Testing No microbial contamination Pass Net Peptide Content Actual peptide mass per vial verified HPLC PURITY 99% IDENTITY Mass-spec confirmed ENDOTOXIN (LAL) Pass LAB Freedom Diagnostic Research Use Only
The EC50 in the above example is 1.3 nM (11.7 ng/mL)
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