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The TCF7L2 Gene: The Most Important Diabetes Gene You've Never Heard Of What it does to your GLP-1 system In 2006, scientists discovered that a variant in TCF7L2 was the strongest genetic risk factor for type 2 diabetes ever found in large population studies confirmed in hundreds of studies across multiple ethnicities, including South Asians
[1] According to NICE guidance (TA875), Wegovy is recommended for use within specialist weight management services with multidisciplinary support
Menopausal women lose muscle mass at an accelerated rate, and muscle tissue is the primary driver of resting metabolic rate
[7] [9] Additionally, GLP-1 medications have effects throughout the gastrointestinal tract, as GLP-1 receptors are widely distributed in the gut
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