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Recent studies have shown that both ephedrine and pseudoephedrine are able to reduce fat accumulation by increasing the levels of down-regulators of the lipogenic transcriptional factors, such as sterol regulatory element-binding protein 1C (SREBP1C), peroxisome proliferator-activated receptor gamma (PPAR), and CCAAT/enhancer-binding protein (C/EBP) [63, 64]
GLP-1 medications accelerate weight loss, which means muscle loss is a real and common concern
Because people with HIV often experience accelerated aging even when the virus is well controlled, this was a population where we might expect a metabolic intervention to register a measurable signal, so the direction was plausible
Melanocortin 2 receptors (MC2Rs) are found in the cortex of the adrenal glands and trigger the production of cortisol by these glands
Dietary fibre from whole grains, vegetables, fruits, and legumes represents another key category, aligning with NHS and SACN recommendations for 30g of fibre daily
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