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Semaglutide and tirzepatide, available through licensed 503A compounding pharmacies at PlexusDx, work by activating GLP-1 receptors in the brain to reduce hunger signals and increase feelings of fullness
A previous study from 2024 found participants prescribed semaglutide for diabetes were four times more likely to develop NAION
Movement: Walking for 15 minutes after a meal physically massages the intestines and promotes motility
Why it matters: Dehydration worsens constipation, fatigue, and can be dangerous if you're also experiencing vomiting or diarrhea
For patients with high cardiovascular risk, the protective effects of GLP-1 receptor agonists typically justify continued therapy in the absence of concerning symptoms
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