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These drugs are thought to work by engaging part of the brain called the hypothalamus, which helps regulate a wide variety of hormones, said Dr

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Relevant for clinical practice, our findings show that treatment with semaglutide lowered the risk of MACE compared to sitagliptin, while tirzepatide showed at least comparable benefit to dulaglutide, an older GLP-1 receptor agonist with established cardiovascular efficacy

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