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Although this study provides valuable insights into the effectiveness and potential mechanisms of different iron supplementation strategies by establishing IDA rat models of physiological anemia during pregnancy and post-IDA pregnant rats, there are still some limitations that need to be clarified: First, the rat models used have significant differences from humans in terms of pregnancy cycle, iron metabolism rate, and placental structure

This specific criterion was applied to maintain a strict focus on synthesizing pro-tumorigenic mechanisms, rather than to negate the context-dependent, dual roles of ROS in cancer biology

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