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Given that pancreatic islets have low antioxidant capacity [33] and ROS have been proposed as metabolic coupling factors for insulin secretion [34, 35], we investigated islet ROS levels in Taz -KD mice
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Todays results, especially when combined with those from the STEP-HFpEF trial, open a new chapter of targeting obesity as a new and effective treatment strategy in patients with obesity-related HFpEF, both with and without diabetes. Click here to read the full analysis in the New England Journal of Medicine
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