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Thats one of the big questions moving forward, Habegger said

It is possible that, in addition to factors such as reduced alcohol consumption, weight loss-related improvements in body image, or relief associated with better glycemic control in diabetes, there may also be direct neurobiological mechanisms involved -- for example, through changes in the functioning of the brain's reward system," said study author, Markku Lhteenvuo Research Director at the University of Eastern Finland, in a press release

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doi:10.1001/jamainternmed.2025.5684 7