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For context, headache rates with tirzepatide and semaglutide are similar or slightly higher, suggesting this is more of a general weight-loss medication effect than something specific to cagrilintide pharmacology

[6] [7] At millimolar concentrations, they may also modulate the redox state of the NMDA receptor complex

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Hydrophobic Interactions When Hydrophobic molecules are in a water medium they tend to clump together to limit the surface interaction between the water molecules and hydrophobic molecules