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Histone lysine acetyltransferase inhibitors: an emerging class of drugs for cancer therapy

Blocking FOXO4, which inhibits the activation of P53, causes senescent cells to undergo apoptosis by P53 activation, without affecting healthy cells around them, and has anti-aging effects which may have potential applications in the treatment of numerous age-related diseases, as well as an adjunct to treatment for certain forms of cancer

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Individuals with gastrointestinal disorders like celiac disease, Crohn's disease, or surgical alterations in the gastrointestinal tract may also experience impaired B12 absorption