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Expecting vision improvements within days when mechanism requires months leads to inappropriate discontinuation
Pushing the needle through the opening on a vial dulls the needle, so putting a new needle on the vial will make for an easier injection
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Skin mast cells carry MRGPRX2, a receptor that fires on cationic, aromatic ("cationic amphiphilic") molecules and releases histamine redness, swelling, the classic wheal. It is confirmed for SS-31, which activates the receptor well below its injection concentration
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