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Short half-life GLP-1 drugs can have short half-lives, which may limit their efficacy even with frequent dosing

However, this also makes it challenging to distinguish whether GLP-1RAs exert their effects by directly regulating immune cells or indirectly improving metabolic parameters

Even with the large firm category (those with 200 or more workers), 81% of the employer weight is driven by firms with 200-999 employees

Clinical Trial Results The clinical trial SURMOUNT-5 (NCT05822830) of adults with obesity who did not have type 2 diabetes demonstrated that Zepbound patients had an average weight loss of 50.3 lbs (22.8 kg), which was 20.2% of their body weight, and a 7.2-inch ( 18.4 cm) reduction in waist circumference, at 72 weeks

So what you eat (and when) becomes even more important