The main culprit here is usually an excess of sebum, which can occur when the body produces greater amounts of certain hormones
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Fukami K, Yamagishi S, Sakai K, Kaida Y, Yokoro M, Ueda S, Wada Y, Takeuchi M, Shimizu M, Yamazaki H, et al
These changes in gene expression are dependent on the time interval during which the genes were analyzed, as well as the type of vessel investigated