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These observations may be due in part to the improved oxygenation and normalization of erythropoietin production observed with SGLT2i (79) and observed renoprotective effects (80)

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BI 456906 (survodutide), developed as a dual agonist for GLP-1 and glucagon receptors for the treatment of obesity and NASH, is structurally modified from glucagon [109]

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