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The state of ketosis, induced by low insulin levels, may generally benefit cancer patients, as KBs have been shown to inhibit glycolysis in various tumor cell lines 73, 74 and probably also patients, 75, 76, 77 and tumor cells often lack the enzymes 78, 79, 80, 81 or oxygenation 82 to effectively use ketones for energy production

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FDG is used as a surrogate for glucose in PET studies to provide an estimate of glucose uptake by the brain across the bloodbrain barrier via solute carrier family 2, facilitated glucose transporter member 1 (GLUT1)

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