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In a clinical trial, pure genistein supplementation (54 mg/day, P.O for one year) improved both cardiac function and left atrial remodeling in postmenopausal women with metabolic syndrome [138]
Pivotal trial result: AOD-9604's Phase 2b trial (536 subjects, 24 weeks) failed its primary endpoint
[1] It is particularly common in certain parts of Africa, Asia, the Mediterranean, and the Middle East
The pathogenetic role of oxidative stress in NALFD is well known and would explain the rationale for the use of GSH as a potential therapy
doi: 10.1016/j.resmic.2013.03.009 135 JametA.JoussetA
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