A prospective proof-of-concept study by Nicolau et al 19 found that liraglutide treatment for three months resulted in a decrease in BMI (from 39.3 to 35.6 kg/m 2 ), waist circumference (from 121.3 to 110.6 cm), mean Hurley stage (from 2.6 to 1.1), DLQI (from 12.3 to 9.7), Beck Depression Inventory (BDI) (from 22 to 16.7), and visual analog scale (VAS) for pain (from 5.6 to 3.2), as well as a decrease in inflammatory markers such as CRP (from 4.5 to 3 mg/dL), homocysteine (from 16.2 to 13.3 mol/L), plasma morning cortisol (from 15.9 to 12.6 g/dL), and insulin (from 18.9 to 15.7 U/mL)
The good news with Retatrutide is that the side effect profile improves significantly with time
Hypersensitivity reactions anaphylactic reactions and angioedema have been reported
Neuroimage Rep 2:100095 Heine J, Schwichtenberg K, Hartung TJ, Rekers S, Chien C, Boesl F, Rust R, Hohenfeld C, Bungenberg J, Costa AS, Scheibenbogen C, Bellmann-Strobl J, Paul F, Franke C, Reetz K, Finke C (2023) Structural brain changes in patients with post-covid fatigue: a prospective observational study
The purpose of the present study is to meta-analyze data pertaining to regarding the effects of GLP-1 based therapies on markers of atherosclerosis observed in related clinical trials