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BSO treatment showed increased expression of Dnmt3a and 3b and decreased Tet2 and 3 transcripts, and it was not wholly restored after treatment withdrawal at different time points, as was shown by real-time PCR analyses (Fig
Semaglutide (Wegovy) for weight management
Diabetes Care 40: 117-124
These findings largely align with whats been seen with tirzepatide and other GLP-1based medications, including small risks of pancreatitis and gallbladder issues, dose-related gastrointestinal side effects, and discontinuation due to tolerability
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