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10.1111/bjh.15038 Br
Br J Cancer 116(8):990993 Ksters-Vandevelde HV, Willemsen AE, Groenen PJ, Ksters B, Wesseling ML, Djafarihamedani M et al (2014) Experimental treatment of NRAS-mutated neurocutaneous melanocytosis with MEK162, a MEK-inhibitor
An excess of loosely bound copper in such a system produces oxidative stress, and oxidative stress produces transcriptional and proliferative changes that are easily read as biological activity of the compound
The column was pre-equilibrated at a flow rate of 0.1 mL/min until a stable baseline and system pressure were achieved, after which 20 L of each sample was injected and analyzed by SEC at 0.2 mL/min with a total run time of 30 min
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