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Many patients begin to notice changes within the first few weeks when treatment is combined with dietary and lifestyle changes

In adults with overweight or obesity (without diabetes) the semaglutide 2.4 mg dose produced an average weight reduction of about 15% of baseline body weight over ~68 weeks in the STEP 1 trial, a result that surprised many clinicians because it brought pharmacologic outcomes into a range previously associated with surgical interventions

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Bodyweight exercises, resistance bands, and even loaded carries or stair climbing all count

It plays several important roles: Helping maintain healthy blood sugar levels after meals Supporting a feeling of fullness and satisfaction Regulating appetite and digestion When GLP-1 activity is healthy, it may help reduce cravings, support balanced energy, and contribute to gradual, sustainable weight management