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In head-to-head trials, tirzepatide users lost approximately 15.3% of body weight in one year, compared to 8.3% with semaglutide

Dosing is flexible, allowing for extension of dose-escalation intervals, dose reduction, and treatment pauses

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Tirzepatide achieved mean weight loss of 10.2kg versus 3.2kg for semaglutide at 52 weeks

But I think its important to contribute to the conversation as someone who has long fallen in the middle, both in my weight and my feelings about weight-loss drugs