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Although high doses of B12 are generally considered safe due to its water-soluble nature, most individuals can obtain sufficient B12 through a balanced diet that includes foods like meat, eggs, and fortified cereals

Some patients report headache, changes in sleep patterns, mild nausea, or mood fluctuation during the first week

For individuals with pre-existing gastrointestinal conditions such as inflammatory bowel disease, previous bowel surgery, or chronic constipation, closer monitoring may be warranted when initiating therapy