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In a double-blind trial, 1961 non-diabetic adults with a body-mass index (the weight in kilograms divided by the square of the height in meters) of 30 were randomly assigned in a 2:1 ratio, to 68 weeks of treatment with once-weekly subcutaneous semaglutide (at a dose of 2.4 mg) or placebo, plus lifestyle intervention

It combines two ingredients, bupropion and naltrexone

The specificity of these effects is in agreement with prior studies showing that the consequences of emotional maltreatments in childhood differ from those of physical and sexual abuse [56, 57]

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Brody M.D., is a board-certified endocrinologist and fellowship-trained reproductive endocrinologist