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D.FungV.et al
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While these trials excluded patients with a formal diagnosis of type 2 diabetes, its highly plausible that a substantial proportion of participants had early metabolic abnormalities, such as insulin resistance , elevated fasting insulin , or even undiagnosed prediabetes
Therefore, when the treatment stops, melanin production may return to normal, eventually turning the skin back to its original color
In mouse models, GLP-1R agonists have been shown to mitigate inflammation in contexts ranging from colitis to cardiovascular injury ( 5 )
Sonthalia S, Jha AK, Lallas A, Jain G, Jakhar D
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