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This will confirm my understanding with respect to the shares to be issued to me by reason of this exercise of the Options (the shares to be issued pursuant hereto are collectively referred to hereinafter as the Shares ), as follows: (a) I am purchasing the Shares for my own account for investment only, and not with a view to, or for sale in connection with, any distribution of the Shares in violation of the Securities Act of 1933, as amended (the Securities Act ), or any rule or regulation under the Securities Act

Moreover, the genera Roseburia and Megamonas were higher, and Escherichia/Shigella was lower in benign brain tumours than malignant brain tumours [183]

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