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It's also a good idea to keep pens in their original box for extra protection from light

Citations Citations to this article as recorded by Trends in nephrology: kidney metabolism as a therapeutic target Jessica S Kleer, Markus M Rinschen Nephrology Dialysis Transplantation.2026

doi:10.1093/nutrit/nuad027

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If the reconstituted solution appears cloudy, has visible particulates, or has changed color, it's a clear sign of contamination or severe degradation