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Similarly, another 12-week randomized controlled trial using a multi-strain probiotic (SanProbi Barrier) containing nine Lactobacillus and Bifidobacterium strains demonstrated notable improvements in thyroid-stimulating hormone (TSH), androstenedione, SHBG, and BMI among PCOS patients, particularly in those with high free androgen index (FAI) index phenotypes (109)

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