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In this cohort study, most patients with overweight or obesity discontinued GLP-1 RA therapy within 1 year, but those without type 2 diabetes had higher discontinuation rates and lower reinitiation rates, the researchers concluded

18 Similarly, in another exploratory analysis, researchers compared TMAO and its precursor in 56 subjects with paroxysmal AF and 22 individuals suffering from persistent AF and detected a significant relationship between TMAO levels and AF progression phenotypes without difference in precursors, which was the first time to confirmed the relationship between TMAO and the progression of AF

Combination therapy with an SGLT2 inhibitor as initial treatment for type 2 diabetes: A systematic review and meta-analysis

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