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Efficacy magnitude Clinical trials show GLP-1 agonists produce substantial HbA1c reductions (typically 1.01.5% depending on agent and dose) and weight loss (515% of body weight with higher doses)

In the gut, GLP-1 binding to its receptors can slow down the emptying of the stomach, which can also help to reduce food intake and promote weight loss

[5] [6] The unusual gamma amide linkage in glutathione protects it from hydrolysis by peptidases

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