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Due to these adverse effects, some individuals should be cautious when taking CLA supplements until more studies can be done

[16] [17] Cambios en otras condiciones mdicas: Si desarrolla enfermedad renal, problemas de vescula biliar, o cualquier otra condicin mdica significativa mientras toma agonistas GLP-1, informe a su mdico

Overall, no clear benefit on ventricular function has been demonstrated, but some trials have found coenzyme Q 10 supplementation improved exercise capacity and reduced mortality

Furthermore, in a 12-week RCT in which patients were either assigned to liraglutide (1.8 mg/day), sitagliptin (100 mg/day) or placebo, no difference in glycemic control or bodyweight reductions were found, and both treatments failed to reduce liver hepatic fat content compared to placebo (69)

The 15mg dose in a controlled 28-week trial yielded 7.38 percent loss