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When detoxification capacity is overwhelmed: Oxidative stress rises Mitochondrial efficiency declines Cellular recovery slows Pain sensitivity increases This creates a compounding effect: impaired detoxification further strains nutrient reserves, and diminished nutrient reserves reduce detox efficiency

Family History of MTC or MEN2 : For people with a family history of MTC or MEN2 but no personal diagnosis, it may still be safe to proceed with caution

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M., Violante, S., Ventura, F