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Mol.Genet.Metab 2008;94(3):287-291
MC4R activation also modulates noradrenergic and serotoninergic neurotransmission, reflecting the multi-neurotransmitter landscape of hypothalamic sexual behaviour regulation
Explanations for this can include: An increase in luteal phase progesterone
(131) proved the neuroprotective efficacy of intracerebroventricular injection (i.c.v.) of Ex-4 exerted after transient ischemia/reperfusion in rats and first suggested that Ex-4 played a neuroprotective role probably by stimulating the GLP-1R/-endorphin signal pathway in hippocampal microglia (76)
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