Additionally, because Ipamorelin is a selective growth hormone secretagogue, it does not increase plasma levels of cortisol, the stress hormone, or adrenocorticotropic, another hormone originating in the pituitary gland
It also counteracts the increased appetite that follows weight loss [112, 113]
Clinical review and treatment plan: A licensed clinician trained in obesity medicine reviews your information, determines whether labs are needed, and builds a treatment plan
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Semaglutide 2.4mg (GLP-1 Agonist): Proven GLP-1 effects (appetite suppression, gastric emptying) Already FDA-approved as Wegovy Established safety profile Cagrilintide 2.4mg (Amylin Analog): Mimics amylin, a hormone co-secreted with insulin Slows gastric emptying through different pathway than GLP-1 Reduces appetite through hindbrain (not hypothalamus) Improves postprandial glucose The Advantage: Leverages proven semaglutide efficacy and safety, adds complementary amylin effects