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However, the chronic fat-reducing effects appear entirely dependent on beta-3 receptor function, indicating this is the primary pathway for sustained fat loss
Tirzepatide (Zepbound) received FDA approval in December 2024 for moderate-to-severe obstructive sleep apnea in adults with obesity, based on the SURMOUNT-OSA trials published in the New England Journal of Medicine (Malhotra et al., 2024)
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