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Raw Material Crisis: API Prices Surge 200300% Date: March 2227, 2026 The ongoing West Asia conflict continues to disrupt supply chains, significantly increasing pharmaceutical production costs
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2 Vital role of mitochondria in AS 2.1 Mitochondrial dysfunction During AS progression, mitochondrial dysfunction is associated with progressive deleterious changes, including 1) the accumulation of mtDNA mutations, 2) excessive production of mtROS and diminished antioxidant defense, leading to increased oxidative damage, and 3) mitophagy inhibition, leading to a decline in mitochondrial renewal
Key highlights Metformin is a first-line oral medication for the management of type 2 diabetes
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