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Chronic stress elevates cortisol, which promotes fat storage (especially visceral belly fat) and interferes with fat loss even when youre in a calorie deficit

A quarter century ago, the term Social Determinants of Health was coined, defined as the non medical factors that inuence health, too often ignored by the medical establishment, such as poverty

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Most clinicians would recommend maximizing results with a single agent before adding complexity, particularly given that tirzepatide already produces substantial fat loss on its own