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Vitamin B12 deficiency can cause macrocytic anaemia, peripheral neuropathy, cognitive impairment, and fatigue

Ascorbate, dithiothreitol and TCEP all reduce copper(II) to copper(I), and the donor arrangement in this tripeptide stabilizes the divalent ion specifically

Practical takeaway: aim for a mix of fresh and frozen produce, and keep cooking simple

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[3] Another review of 14 randomized controlled trials also did not consistent evidence of benefit with the use of vitamin B12 supplements, alone or with other B vitamin supplements, on cognitive function in people with either normal or impaired cognition