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Regarding thyroid safety: GLP-1 receptor agonists as a class have been associated with thyroid C-cell tumours in rodent studies, though the relevance of these findings to humans remains uncertain
Within that metabolic field 5-Amino-1MQ occupies a distinct place: it is not a peptide, but a small research molecule described in research models as an inhibitor of the enzyme NNMT, which makes it of interest within NAD+ focused metabolic research
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This is why tracking caloric intake matters even when you are not hungry
Patients start at 2.5 mg weekly for 4 weeks, then escalate by 2.5 mg increments every 4 weeks as tolerated until reaching maintenance dose, typically 10 mg or 15 mg
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