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One of those is the dreaded Ozempic face that many celebrities are seen with: a hollowed-out, saggy appearance resulting from rapid weight loss

* **Noticeable Weight Loss:** Significant and measurable weight loss typically **begins or accelerates once you reach and maintain therapeutic doses (5 mg and higher).** Most of the substantial weight loss seen in clinical trials occurred at the higher maintenance doses (5 mg, 10 mg, and 15 mg)

Pattern 2: gradual gain of 1 to 2 pounds per week over 4 or more weeks Most likely cause: Calorie creep plus metabolic adaptation

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The nerve cell loses its ability to produce ATP